Table 3 Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and balanced accuracy for prespecified high-risk thresholds for a logistic regression model containing established risk factors only (Old model), a logistic regression model containing both established and additional risk factors (New model), and ensemble model in the test dataset.

From: A five-year risk prediction model of cardiovascular disease in individuals with bipolar disorder: a nationwide register study from Sweden

Threshold

Sensitivity

Specificity

PPV

NPV

Balanced accuracy

0.1/10%

Old model

0.67 (0.63, 0.71)

0.74 (0.73, 0.75)

0.19 (0.18, 0.21)

0.96 (0.95, 0.97)

0.704

New model

0.67 (0.63, 0.70)

0.74 (0.73, 0.75)

0.19 (0.18, 0.21)

0.96 (0.95, 0.96)

0.704

Ensemble model*

0.65 (0.61, 0.69)

0.75 (0.73, 0.76)

0.19 (0.18, 0.21)

0.96 (0.95, 0.96)

0.697

0.2/20%

Old model

0.29 (0.26, 0.33)

0.93 (0.92, 0.93)

0.27 (0.24, 0.31)

0.93 (0.93, 0.94)

0.610

New model

0.31 (0.27, 0.35)

0.92 (0.92, 0.93)

0.28 (0.24, 0.31)

0.93 (0.93, 0.94)

0.617

Ensemble model*

0.23 (0.20, 0.26)

0.96 (0.95, 0.96)

0.33 (0.29, 0.38)

0.93 (0.92, 0.94)

0.593

  1. *Ensemble model includes all 63 predictors.