Fig. 4: Liver Enzymes, Long-Term January 2005-August 2024 and Pre vs Post October 7th. | Molecular Psychiatry

Fig. 4: Liver Enzymes, Long-Term January 2005-August 2024 and Pre vs Post October 7th.

From: Intensity and exposure proximity as determinants of differential stress-related health outcomes

Fig. 4: Liver Enzymes, Long-Term January 2005-August 2024 and Pre vs Post October 7th.

A GGT were elevated chronically and signficantly specifically in high exposure men 46–64 (bottom, center) in years of escalation (2007, 15 s vs 90 s, p < 0.001; 2009, 15 s vs 90 s p < 0.001; 2019, 15 s vs 90 s, p < 0.001, d = 0.42), while women 46–64 showed peak levels in 2019 (15 s vs 90 s, p < 0.001, d = 0.40). Men 19–45 elevations with a d = 0.27 (2008–2009, 15 s vs 90 s, p < 0.001; 2011, 15 s vs 90 s, p < 0.001; 2013–2014, 15 s vs 90 s, p < 0.01; 2022, 15 s vs 90 s, p < 0.001). Men 19–45 had highest post-October 7th levels (lower, left, inset, 15 s post vs 90 s post, 15 s post avg, 60.521, SD 13.5, 90 s post avg, 35.9, SD 0.47, p < 0.0001). B ALT were also chronically elevated in 15 s in both men (46–64, peak 2019 p < 0.001, d = 0.28, bottom, center panel) and in women 19–45 had particulary high elevation in 2016, (15 s vs 90 s p < 0.001, d = 0.37), while women 46–64 had elevations from from 2013–2022 (15 s vs 90 s p < 0.01). Post-October 7th, males 19–45 in all shelter times had elevations (p < 0.01, 15 s pre vs 15 s post, d = 0.20; 30 s pre vs 30 s post, 90 s pre vs 90 s with small d = < 0.20) (C) Alkaline Phosphate (Alk Phos) levels, also increased significantly pre vs post October 7th in every age group (insets), gender and shelter time, even low exposure (men, 19–45, 46–64, 65+, p < 0.001,15 s pre vs 15 s post; p < 0.001 30 s pre vs 30 s post ; p < 0.001, d up to 0.35). D In AST had significant changes within each shelter time pre vs post October 7th in the same direction of elevation in all ages except 15 s males over age 65 + , with highest d = 0.2 in women ages 46–64 (p < 0.001, 30 pre vs 30 s post).

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