Fig. 5 | Mucosal Immunology

Fig. 5

From: Goblet cell associated antigen passages are inhibited during Salmonella typhimurium infection to prevent pathogen dissemination and limit responses to dietary antigens

Fig. 5

Pretreatment with oral antibiotics that induce colonic GAPs, but not with those that do not induce colonic GAPs, increases Salmonella dissemination and reduces survival. a Salmonella in the colon contents and b CFUs in the colon-draining MLN and c Kaplan–Meier survival curves in untreated C57BL/6 mice or C57BL/6 mice pretreated with neomycin (500 µg), tetracycline (500 µg), streptomycin (500 µg), or vancomycin (250 µg) 1 day prior to infection with 5 × 107 CFU Salmonella. Data represented as the mean ± SEM; *p < 0.05, ns = not significant, n = 5 or more mice.

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