Fig. 2
From: Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis
AIEC colonization promotes intestinal fibrosis in Salmonella-infected mice. S. Typhimurium ΔspiA (ST) and E. coli (HS or LF82) infected mice were sacrificed on day 2 (a) and on day 21 post ST infection (b–e). Colonic tissues were harvested on day 2 (a) and on day 21 (b, c) post ST infection and mRNA expression of indicated cytokines were quantified by qPCR. The accumulation of collagen was examined by Picrosirius red staining on day 21 post ST infection (d) and collagen assay (e). Dots represent individual mice. Bars represent mean. N.S.; not significant, *; P < 0.05, **; P < 0.01, ***; P < 0.001 by 1-Way ANOVA with Bonferroni post-hoc test
