Fig. 7 | Mucosal Immunology

Fig. 7

From: Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens

Fig. 7

IRF5Δmye mice demonstrate less effective clearance of oral S. Typhimurium infection. IRF5WT or IRF5Δmye mice (n = 7–11; 2.5–3 months of age) were orally inoculated with S. Typhimurium and assessed 5 days later. a S. Typhimurium CFU. b Colon myeloperoxidase. c Colon cytokines. d Serum cytokines. Representative of 3 independent experiments. Mean + SEM. *p < 0.05; **p < 0.01; ***p < 0.001; p < 1 × 10−4; ††p < 1 × 10−5

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