Table 1 Characteristics of study population (RT-qPCR study) (n = 92).
From: The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD
Never smokers | Smokers without COPD | COPD GOLD II | COPD GOLD III–IV | |
|---|---|---|---|---|
Number | 18 | 26 | 34 | 14 |
Gender ratio (male/female) | 6/12# | 19/7# | 31/3# | 8/6# |
Age (years) | 65 (56–70) | 63 (55–70) | 66 (58–69)§ | 56 (54–60)*§† |
Current-/ex-smoker | – | 16/10 | 22/12 | 0/14 |
Smoking history (PY) | 0 (0-0) | 28 (15–45)* | 45 (40–60)*§ | 30 (25–30)*† |
FEV1 post (L) | 2,7 (2.3–3.2) | 2,7 (2.3–3.3) | 2.0 (1.8–2.4)*§ | 0.7 (0.7–0.9)*§† |
FEV1 post (% predicted) | 102 (92–116) | 95 (93–112) | 68 (61–75)*§ | 26 (20–32)*§† |
FEV1/FVC post | 78 (75–83) | 75 (71–79)* | 56 (53–60)*§ | 32 (27–35)*§† |
DLCO (% predicted) | 90 (80–105) | 80 (61–102) | 67 (51–87)* | 35 (33–41)*§† |
KCO (% predicted) | 103 (88–123) | 91 (68–107)* | 87 (62–108)* | 59 (50–65)*§† |
ICS (yes/no) | 0/18# | 1/25# | 15/19# | 13/1# |
