Table 2 Clinical status evaluation in experimental piglets.

From: Secretory IgA N-glycans contribute to the protection against E. coli O55 infection of germ-free piglets

Scale

Scaled parameter

Temperature

Volume per feeding

Stool

Interest

1

normal range 36.7–37.7 °C

≥15 ml

Normal

Active movement, active response to stimuli

2

enhanced temperature 37.8–39.5 °C

<15 ml

Diarrhea

Still standing, weak response to stimuli

3

fever 39.5–41 °C

0 ml

–

Lying, lethargy

4

temperature declining < 39.5 °C

–

–

Trembling

5

hypothermia < 36.7 °C

–

–

Death

  1. Each parameter (temperature, volume per feeding, stool quality, interest) was scored independently for each piglet (Supplementary Table 1) and overall clinical status was evaluated as weighted mean for each piglet. The weight for temperature was 0.4, for drink volume 0.2, for stool 0.2, and for interest 0.4.