Fig. 5: Bone marrow-derived macrophages (BMDMs) treated with XOI during RSV infection show decreased expression of IL-1β and CCL2. | Mucosal Immunology

Fig. 5: Bone marrow-derived macrophages (BMDMs) treated with XOI during RSV infection show decreased expression of IL-1β and CCL2.

From: Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation

Fig. 5

a qPCR XO expression in BMDMs that were RSV infected. b, c Expression and production of IL-β by BMDMs treated with or without XOI during RSV infection. d, e CCL2 expression and production in BMDMs treated with or without XOI during RSV infection. f, g Expression of IL-1β and CCL2 in BMDMs treated with uric acid during RSV infection. Data represent the Mean ± SE from 4 replicates per group (experimental repeats 3). *p ≤ 0.05, **p ≤ .01, ***p ≤ 0.001.

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