Table 1 The effect of neutrophil depletion in mice on viral load, weight loss and lung pathology during multiple respiratory viral infections.

From: Neutrophils in respiratory viral infections

Virus

Viral load

Weight loss/clinical score

Pathology and cell infiltration

Viral strain

Species and strain

Refs.

IAV

–

–

?

X31

Mouse; BALB/c

58

IAV

↑

↑

↑

X31

Mouse; C57BL/6

44,65

IAV

↑

↑

?

PR8

Mouse; C57BL/6

65

IAV

–

–

–

PR8

Mouse; BALB/c

160

IAV

–

↑

?

PR8

Mouse; C57BL/6

66

IAV

–

↑

?

PR8

Aged mice; C57BL/6

66

PVM

–

–

–

J3666

Mouse; BALB/c

24

PVM

–

–

–

J3666

Mouse; C57BL/6

24

RSV

–

?

?

2-20

Mouse; BALB/c

177

RSV

–

–

?

A2

Mouse; C57BL/6

176

HMPV

–

↑

↑

CAN97-83

Mouse; BALB/c

4

MCMV

↑

↑

?

Smith strain

Mouse; C57BL6

27

rCoV

↑

↑

↓

Sialodacryoadenitis virus

Rat; Fisher 344

13

  1. – no difference; ↑increase; ? not evaluated.