Fig. 1: Knockdown of PTPN2 abolished the intracellular response to IL-6. | Mucosal Immunology

Fig. 1: Knockdown of PTPN2 abolished the intracellular response to IL-6.

From: Loss of protein tyrosine phosphatase non-receptor type 2 reduces IL-4-driven alternative macrophage activation

Fig. 1: Knockdown of PTPN2 abolished the intracellular response to IL-6.

THP-1 cells expressing either non-targeting control (shCtr) or PTPN2-specific (shPTPN2) shRNA were differentiated into macrophages and subsequently treated for the indicated time with a 20 ng/ml IL-6 or b 50 ng/ml EGF. Depicted are representative Western blot images for the indicated proteins from five independent experiments (n = 5).

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