Table 1 Summary of single-cell multi-omics technologies.

Transcriptome and genome

RNA and gDNA

G&T-seq,¹⁴ DR-seq,¹⁵⁶ SIDR,¹⁵⁷ TARGET-seq¹⁵⁸

Transcriptome and epigenome

Poly-A mRNA and gDNA methylation

scM&T-seq,¹⁵⁹ scMT-seq¹⁶⁰

Poly-A RNA (nuclear) and chromatin

SNARE-seq,¹⁶¹ sci-CAR,¹⁶² Paired-seq¹⁶³

Poly-A RNA, gDNA methylation, and chromatin

scNMT-seq¹⁶⁴

Transcriptome, genome, and epigenome

Poly-A mRNA, CNVs, and gDNA methylation

scTrio-seq¹⁶⁵

Transcriptome and proteome

RNA and targeted proteins

CITE-seq,¹⁶⁶ PLAYR,¹⁶⁷ PEA/STA,¹⁶⁸ REAP-seq,¹⁶⁹ RAID,¹⁷⁰ INs-seq¹⁷¹

Transcriptome, epigenome, and proteome

RNA, chromatin, and targeted proteins

TEA-seq¹⁷²

Transcriptome, genome, epigenome, and proteome

RNA, chromatin, mitochondrial DNA, and targeted proteins

DOGMA-seq¹⁷³

Transcriptome, proteome, clonotypes, and CRISPR perturbations

Poly-A RNA, sgRNA, and targeted cell surface proteins

ECCITE-seq¹⁷⁴