Fig. 1: Expression of NmU and NmUR1 in human samples. | Mucosal Immunology

Fig. 1: Expression of NmU and NmUR1 in human samples.

From: Neuromedin U promotes human type 2 immune responses

Fig. 1

a hNmU-25 levels in human plasma and sputum supernatants from healthy subjects or patients with asthma were detected by ELISA. b Comparison of NmUR1 expression in different human immune cells from fresh blood determined with flow cytometry. c NmUR1 expression in CRTH2+ (type 2 lymphocytes: Th2, Tc2 and ILC2) and CRTH2- lymphocytes (other Th, Tc, and ILC). The expression levels in type 2 cells were compared with gMFI. d, e NmUR1 expression in ILC subsets (d) or in ILC2 subsets (e). f–h NmUR1 expression in Th2 (f), Tc2 (g) and ILC2 (h) cells in fresh blood among healthy controls (healthy), non-eosinophilic (non-eos) and eosinophilic (eos) asthma groups was compared. *p < 0.05, **p < 0.01, ***p < 0.001, ***p < 0.0001.

Back to article page