Fig. 5: Expression of Creb5 in exacerbation lung, macrophage, and DC populations. | Mucosal Immunology

Fig. 5: Expression of Creb5 in exacerbation lung, macrophage, and DC populations.

From: Single-cell RNA transcriptomic analysis identifies Creb5 and CD11b-DCs as regulator of asthma exacerbations

Fig. 5

a Seurat-UMAP cluster analysis showing displaying Creb5 populations between control (SAL and CTRL) and exacerbation (H/HDM, H/CRE, and H/RSV) groups. b Fold-change expression of Creb5 determined by qPCR analysis in mouse lungs relative to HPRT. Values are represented as mean ± SEM, n = 6–8. c Fold-change expression of Creb5 in purified cell populations isolated by factors (±CD11c DCs, ±MHCII macrophages) relative to HPRT. Values are represented as mean ± SEM, n = 4. #Designates significant differences compared to both SAL and HDM groups (#p < 0.05). *Designates significant differences compared to SAL group (*p < 0.05).

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