Table 1 Demographic and clinical characteristics of subjects with MDD and controls and in SSRI responders and non-responders

From: Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

 

Controls N = 55

MDD N = 50

P-value

Responders N = 11

Non-responders N = 8

P-value

Sex (f/m)

33/22

27/23

0.54

8/3

5/3

0.64

Age (Years; mean ± SD)

37.6 ± 13.9

39.6 ± 14.7

0.47

39.2 ± 12.6

39.0 ± 14.9

0.98

BMI (kg/m2; mean ± SD)

24.4 ± 4.9

26.1 ± 4.5

0.07

26.2 ± 5.4

30.1 ± 2.7

0.05

Current tobacco users (n)

3

13

 < 0.01

3

2

0.91

HDRS score at baseline (mean ± SD)

N/A

20.2 ± 3.3

N/A

19.8 ± 3.0

19.6 ± 4.0

0.91

  1. HDRS Hamilton Depression Ratting Scale, BMI body mass index
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