Table 2 Effects of oxytocin vs placebo on whole-brain CBF (without adjustment for global CBF effects)
From: Oxytocin modulates hippocampal perfusion in people at clinical high risk for psychosis
Cluster Description | Hemisphere | k | P(FWE-corr) | Peak coordinates | Peak description | ||
|---|---|---|---|---|---|---|---|
x | y | z | |||||
Run 1, Oxytocin > Placebo | |||||||
Left cerebellum, visual cortex, parahippocampal gyrus, hippocampus, fusiform gyrus, lingual gyrus; right cuneus, calcarine gyrus, visual cortex, cerebellum | Left | 3904 | <.05 | −26 | −32 | −36 | Cerebellum (culmen) |
−20 | −46 | −28 | Cerebellum (culmen) | ||||
−24 | −72 | −2 | Lingual gyrus | ||||
Run 1, Placebo > Oxytocin | |||||||
None | |||||||
Run 2, Oxytocin > Placebo | |||||||
Left cerebellum, fusiform gyrus, parahippocampal gyrus, hippocampus, lingual gyrus, thalamus; right cerebellum | Left | 3117 | <.05 | −36 | −44 | −8 | Parahippocampal gyrus |
−2 | −80 | −34 | Cerebellum (pyramis) | ||||
−16 | −58 | −12 | Cerebellum (culmen) | ||||
Right superior parietal lobule, precuneus, calcarine gyrus, cuneus, visual cortex; left visual cortex | Right | 2394 | <.05 | 22 | −60 | 68 | Superior parietal lobule |
8 | −48 | 74 | Postcentral gyrus | ||||
4 | −82 | 28 | Cuneus | ||||
Run 2, Placebo > Oxytocin | |||||||
None | |||||||
Mean of the runs, Oxytocin > Placebo | |||||||
Left cerebellum, parahippocampal gyrus, hippocampus, fusiform gyrus, thalamus, lingual gyrus, visual cortex; right cuneus, visual cortex, cerebellum | Left | 5348 | <.05 | −26 | −32 | −36 | Cerebellum (culmen) |
−26 | −48 | 20 | White matter | ||||
−30 | −48 | 10 | White matter | ||||
Mean of the runs, Placebo > Oxytocin | |||||||
None | |||||||
