Table 2 Adjusted fallypride BPND values in regions of interest in high and low externalizing (EXT) trait score youth (means ± standard errors of the mean).

From: Extra-striatal D2/3 receptor availability in youth at risk for addiction

Regions of interest

High EXT group (N = 27)

Low EXT group (N = 31)

Statistical test*

Partial Eta squared (partial η2)

Superior frontal gyrus

0.69 ± 0.049

0.53 ± .047

p = 0.032

0.085

Middle frontal gyrus

0.85 ± 0.050

0.68 ± .048

p = 0.020

0.10

Medial frontal gyrus

0.79 ± 0.045

0.64 ± .043

p = 0.029

0.088

Orbitofrontal gyrus

1.06 ± 0.050

0.97 ± 0.049 (N = 30; 1 outlier removed)

p = 0.24

0.027

Hippocampus

1.51 ± 0.054 (N = 26; 1 outlier removed)

1.43 ± 0.053 (N = 29; 2 outliers removed)

p = 0.28

0.025

Amygdala

3.29 ± 0.11 (N = 26; 1 outlier removed)

2.95 ± 0.11 (N = 30; 1 outlier removed)

p = 0.038

0.088

Insula

1.70 ± 0.069 (N = 26; 1 outlier removed)

1.49 ± 0.068 (N = 29; 2 outliers removed)

p = 0.048

0.081

Midbrain

1.97 ± 0.073 (N = 26; 1 outlier removed)

1.83 ± 0.070 (N = 28; 2 outliers removed/1 file unavailable)

p = 0.18 (univariate ANCOVA)

0.038

  1. Presented means are adjusted for AUDIT scores, current smoker status (yes/no), occasions of cannabis use (lifetime) and occasions of drug use (lifetime; excluding cannabis, alcohol, and cigarettes) included in the repeated-measures ANCOVA.
  2. *Reflect pairwise comparisons (univariate ANCOVA) of interactions with group as a factor (broken down by group) in the repeated measures ANCOVAs (i.e., group × region), regardless of whether the interaction was significant or not.
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