Table 2 Results from multilevel analyses examining the differential activation of threat neural circuitry ROIs across phases of fear conditioning and associations with symptom dimensions of general distress, fears and anhedonia-apprehension.

From: Dysregulation of threat neurocircuitry during fear extinction: the role of anhedonia

 

Parameter estimate

Confidence interval

p value

Fear acquisition (all CS+ vs. all CS−)

 (Intercept)

0.11

−0.04 0.26

0.143

 General Distress

0.00

−0.06, 0.07

0.947

 Fears

−0.05

−0.12, 0.01

0.121

 Anhedonia-apprehension

0.04

−0.03, 0.10

0.244

Fear extinction (late CS+ vs. late CS−)

 (Intercept)

−0.02

−0.17, 0.14

0.831

 General Distress

−0.01

−0.08, 0.06

0.771

 Fears

−0.02

−0.10, 0.06

0.576

 Anhedonia-apprehension

0.13

0.06, 0.20

0.001*

Extinction recall (early CS+ U vs. early CS+ E)

 (Intercept)

0.16

0.02, 0.30

0.030*

 General Distress

0.01

−0.05, 0.08

0.659

 Fears

−0.06

−0.13, 0.01

0.103

 Anhedonia-apprehension

0.02

−0.04, 0.09

0.491

  1. *p < 0.05.