Fig. 1: Early-life oxytocin increases plasma oxytocin concentration in adulthood. | Neuropsychopharmacology

Fig. 1: Early-life oxytocin increases plasma oxytocin concentration in adulthood.

From: Early-life oxytocin attenuates the social deficits induced by caesarean-section delivery in the mouse

Fig. 1: Early-life oxytocin increases plasma oxytocin concentration in adulthood.

A Schematic representation of OXT treatment and behavioural testing sequence. Following birth by C-Section or per vaginum, pups received daily injections of OXT (0.2 or 2 μg/20 μl saline; s.c.) from postnatal days 1–5 and were subjected to a sequence of behavioural tests. B OXT administration in early-life increases OXT plasma levels in adulthood. Mode of delivery effect (F (1, 41) = 1.116, p = 0.297); treatment effect (F (1, 41) = 5.893, p = 0.006); mode of delivery × treatment (F (2,41) = 0.886, p = 0.420). ([VB control n = 6, VB 0.2 OT n = 7, VB 2 OT control n = 8, CS control n = 10, CS 0.2 OXT n = 8, CS 2 OXT n = 8]). Two-way ANOVA, followed by LSD post-hoc. OXT oxytocin, VB vaginal birth, CS C-section. Male offspring in each group derived from three independent litters.

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