Fig. 2: Behavioral and neurobiological (BOLD response) differences between SUBGROUPs on PFT responded trials across nicotine STATE.
From: Not all smokers are alike: the hidden cost of sustained attention during nicotine abstinence
A In both satiety (green) and abstinence (red), High task performers (HTP, yellow box, 88.68% ± 5.19 SD) show higher accuracy only in the High DEMAND condition compared to Low task performers (LTP, purple box, 51.04% ± 4.72 SD) for responded trials. B PFT-evoked BOLD response clusters with differential activation for the HTP compared to the LTP SUBGROUP for the [correct responses (–) errors of commission] trials contrast at the high DEMAND condition across STATE. These clusters were subsequently used as seeds in a whole-brain seed-based functional connectivity analysis. C Extracted β coefficients from the encircled cluster (averaged across STATE) showing greater sensitivity to errors of commission vs. correct responses in the HTP SUBGROUP and no difference between correct responses and errors of commission for the LTP SUBGROUP. This region has been chosen as an exemplar. For ROI extracts from all clusters see Fig. S3. HTP High Task Performers, LTP Low Task Performers, ROI Region of Interest.
