Fig. 4: Brain (∆FC) and behavior (∆EOm) regression between SUBGROUP*STATE differences (abstinence – satiety) in individual Z-scored FC extracts (averaged over “target” ROI) and in EOm across all DEMAND levels of the PFT.
From: Not all smokers are alike: the hidden cost of sustained attention during nicotine abstinence
A Whole-brain regression analyses starting with seeds at the L Precentral (L Pre, red) and R ventral Insula (RvI, blue) and “targets” in the R orbitofrontal cortex (R OFC) and L superior frontal gyrus (L SFG) respectively (orange). The arrows do not imply directionality or causality. B The z-score FC extract difference (abstinence – satiety) averaged over the R orbitofrontal cortex vs. the difference in the number of EOm for all DEMAND levels of the PFT. The HTPs show a positive relationship between the ∆FC and ∆EOm while the LTPs show a negative relationship for the L Pre↔R OFC. C The z-score FC extract difference (abstinence – satiety) averaged over the L SFG vs. the difference in the number of EOm for all DEMAND levels of the PFT. Both SUBGROUPs show a positive relationship between the ∆FC and ∆EOm for the R v Ins↔L SFG. L Pre Left Precentral gyrus, RvI Right ventral Insula, R OFC Right Orbitofrontal Cortex, L SFG Left Superior Frontal Gyrus, FC Functional connectivity, EOm Errors of Omission.
