Fig. 3: Association between changes in eCB concentrations and neural responses during acquisition training.

a The regression analysis of neural responses to the CS + , compared to the CS- in the right amygdala revealed a positive association with the changes in AEA plasma concentration during acquisition training (for statistics see Table S9). b The regression model of neural responses that increase to the US during acquisition training revealed that an increase in activity in the dorsal ACC was associated with increase in AEA concentration (for statistics see Table S10). T-maps are displayed on an averaged image across the whole sample with a threshold of puncorr < 0.005 for illustrative purposes.