Fig. 3: How may rapid homeostatic plasticity transition to chronic effects?
From: Rapid homeostatic plasticity and neuropsychiatric therapeutics
Figure depicts the transition of rapid homeostatic plastic synaptic potentiation towards more sustained effects via transcriptional processes. In this particular example, rapid plasticity elicited by ketamine triggers phosphorylation of the transcriptional regulator MeCP2, which in turn triggers metaplasticity of the ketamine effect (i.e., second ketamine administration gives rise to an augmented response).
