Fig. 1: Cumulative measures of alcohol and water consumption from 1 h pre- and through 6 h post-intranasal oxytocin treatment. | Neuropsychopharmacology

Fig. 1: Cumulative measures of alcohol and water consumption from 1 h pre- and through 6 h post-intranasal oxytocin treatment.

From: Male-selective effects of oxytocin agonism on alcohol intake: behavioral assessment in socially housed prairie voles and involvement of RAGE

Fig. 1

Significant differences were observed between groups in alcohol intake at 2, 3 and 5 h post-treatment, while differences approached significance at 1 and 4 h (A). Significant differences were also observed in alcohol drink size at the 2 and 3 h time points (C). OXT also affected water intake (B) and drink size (D) at 2 h. Data are presented as mean ± standard error of mean. *p < 0.05, Kruskal–Wallis test. Tx denotes time of treatment. Note: −1 h time point is included to demonstrate lack of differences between groups prior to treatment and is defined as the cumulative measure during the 1 h prior to treatment. Cumulative measures post-treatment begin at the 0 h time point which encompasses the time of treatment (Tx) through the first hour. N: female vehicle = 29, female 5 mg/kg OXT = 13, female 10 mg/kg OXT = 14, male vehicle = 27, male 5 mg/kg OXT = 12, male 10 mg/kg OXT = 16.

Back to article page