Fig. 2: Cumulative measures of alcohol and water consumption 3 h following intranasal oxytocin treatment. | Neuropsychopharmacology

Fig. 2: Cumulative measures of alcohol and water consumption 3 h following intranasal oxytocin treatment.

From: Male-selective effects of oxytocin agonism on alcohol intake: behavioral assessment in socially housed prairie voles and involvement of RAGE

Fig. 2

OXT was observed to selectively decrease measures of alcohol consumption 3 h post-treatment; thus, group comparisons were confirmed. Male prairie voles treated with 5 mg/kg and 10 mg/kg IN OXT consumed significantly less alcohol and displayed smaller drink sizes than their saline control counterparts (A, C). No effect was observed on water intake or drink size (B, D). Data are presented as mean ± standard error of mean. Brackets indicate statistically significant differences between groups at ps < 0.05, Mann–Whitney test. N values are the same as in Fig. 1.

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