Fig. 5: Positive correlation between polygenic score for schizophrenia and aggregate gene expression score for schizophrenia.
From: Polygenic scores for psychiatric disorders in a diverse postmortem brain tissue cohort
Samples of European ancestry are shown on the left (n = 85) and samples with African ancestry are on the right (n = 139). Points represent individual donors color coded by diagnosis. The schizophrenia polygenic scores were constructed using weights from independent samples, and the aggregate gene expression scores were constructed using weights from the Human Brain Collection Core samples (see methods), with gene expression values from dorsolateral prefrontal cortex (DLPFC).
