Fig. 2: Brain region expression patterns of NMDAR subunits.
From: Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry
a Overview of brain regions where expression data were compared and data sets used in the analysis. All images and data were modified from the Brain section of the Human Protein Atlas (proteinatlas.org). Data for distribution of expression levels were derived from quantification of mRNA levels from RNAseq and in situ hybridization experiments as well as protein levels from immunohistochemistry and immunofluorescence experiments [234]. Data was downloaded from v20.proteinatlas.org and was reorganized and replotted with custom python scripts using pandas, matplotlib and seaborn libraries without further data processing. b Heatmaps show relative expression levels for NMDAR subunits. Z-scores reflecting relative expression across brain regions were calculated separately for each gene. Relative expression levels (averaged across brain regions) of each subunit compared to other subunits are plotted to the right of each heatmap.
