Fig. 1: Association of perceived social support with limbic activity in response to negative emotional faces in dependence of childhood maltreatment.

a Coronal view (Left and right: y = −36) of the significant social support x group interaction of the ANCOVA in the amygdala-hippocampus-complex (Left: x = −26, y = −36, z = −2, TFCE_(1,124) = 4033.90, F = 8.97, k = 217, p_FWE = 0.024, η_p²=0.089 ; Right: x = 16, y = −36, z = 8, TFCE_(1,124) = 23703.43, F = 23.84, k = 646, p_FWE = 0.005, η_p²=0.070). Color scale: TFCE value. Separate scales for each hemisphere for detailed resolution of the activity clusters. b Scatterplot depicts the association between activity within the right amygdala-hippocampus-complex derived from the social support x group interaction (x = 16, y = −36, z = 8, TFCE_(1,124) = 23703.43, F = 23.84, k = 646, p_FWE = 0.005, η_p²=0.070) and perceived social support scores in healthy individuals without childhood maltreatment compared to healthy individuals with childhood maltreatment. c Coronal and sagittal view (x = −28, y = −8) of the significant negative association of perceived social support with functional activity within the amygdala-hippocampus-complex in the group without childhood maltreatment (Left: x = −28, y = −8, z = −24, TFCE₍₁₂₄₎ = 231.28, T = 4.05, k = 504, p_FWE = 0.021, r = −0.429; Right: x = 14, y = −38, z = 8, TFCE₍₁₂₄₎ = 325.67, T = 4.27, k = 591, p_FWE = 0.010, r = −0.411). Color scale: TFCE value.