Fig. 2: Representative effects of WS-3, the TRPM8 agonist, on extracellular glutamate levels and beta-band power in WT and TRPM8-KO mice after the seizure inducer injection. | Neuropsychopharmacology

Fig. 2: Representative effects of WS-3, the TRPM8 agonist, on extracellular glutamate levels and beta-band power in WT and TRPM8-KO mice after the seizure inducer injection.

From: Anti-seizure effects of WS-3, a TRPM8 agonist, on focal onset seizure mouse model via reduction of extracellular glutamate levels

Fig. 2: Representative effects of WS-3, the TRPM8 agonist, on extracellular glutamate levels and beta-band power in WT and TRPM8-KO mice after the seizure inducer injection.The alternative text for this image may have been generated using AI.

A Representative changes in glutamate levels, ECoG amplitudes, Beta-band amplitudes, and beta-band power in wild-type (WT) and TRPM8 knockout (TRPM8-KO) mice. B Traces are highlighted by yellow columns. ECoGs at 20 s and 1 s show representative beta-band amplitudes before and after TRPM8 agonist injection in each group. ECoG, electrocorticogram; PG, penicillin G potassium (seizure inducer); TRPM8, transient receptor potential melastatin 8; TRPM8-KO, TRPM8 homozygous knockout; WT, wild type.

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