Fig. 4: Two dimensions of hippocampal hyper-maturity: enhanced postnatal development and accelerated aging.

a A matrix of overlap P values between each pair of datasets. The gene expression patterns of the identified hyper-maturity model mice were compared with those at each time point of postnatal development and aging using the BaseSpace platform, and overlap P values were calculated using the Running Fisher test. b PCA scatter plot based on the overlap P values. The first two principal components explain 49.8% of the variance. Red and blue circles indicate Group 1 and Group 2, respectively, as identified by PCA.