Fig. 2: Changes in voxel based morphometry.

Shown are the developmental changes in brain volumes for males a and females b following early exposure to psilocybin (PSI). Highlighted in red are the difference in whole brain volume for males and females shown as violin plots (median and range) for all 139 brain areas after normalization to correct for different whole brain volumes for each subject and then as a fraction of the voxel volume for each brain area to normalize for the large differences in voxel numbers between brain areas. The estimation plots show the difference between vehicle (open circle) and PSI (closed circle) in the individual brain areas and there mean difference (closed squares). Included in each brain region is the p value and the average mean difference. Below are 3D color coded reconstructions summarizing the significantly different brain regions and their difference between sexes. * p < 0.05, *** p < 0.001.