Fig. 3: Mapping fractional anisotropy differences.

Shown in Fig. 3a. are 2D images of statistical heat maps highlighting the location of brain regions that were significantly different in fractional anisotropy (FA) values between vehicle and PSI. Areas in red denote a significant increase in FA values over vehicle for PSI treatment. The yellow identifies white matter tracts. The 3D color coded reconstructions to the right in Fig. 3b. summarize these regional difference in measures of FA.