Fig. 5 | Oncogene

Fig. 5

From: IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway

Fig. 5

miR-24-3p and miR-214-3p integrated interaction-networks merge in c-myc a Network analysis between miR-24-3p/miR-214-3p and mRNA targets. Lines represent interactions between genes and miRs predicted by the IPA Software: indirect interactions (dotted lines), direct interactions (continuous lines). b TECs treated as indicated were lysed and analyzed for c-myc content, normalized to β-actin content (n = 5) (**p < 0.01, none and EVs vs anti-IL-3R-EVs, antago-miR-24-3p-EVs and pre-miR-214-3p-EVs, one-way ANOVA)

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