Fig. 7 | Oncogene

Fig. 7

From: IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway

Fig. 7

miR distribution in antago-miR-24-3p-EVs and pre-miR-214-3p-EVs. a Dot plot distribution graph of the 15 modulated miRs in antago-miR-24-3p-EVs compared to EVs. Dots represent fold change values for each miR. miR-214-3p (red dot) was found to be significantly upregulated in antago-miR-24-3p EVs (foldchange: 3.80 ± 1.00). b Dot plot distribution graph of the 21 modulated miRs in pre-miR-214-3p-EVs compared to EVs. miR-24-3p (red dot) was found to be almost unmodulated in pre-miR-214-3p-EVs (foldchange: 0.26 ± 0.14). c Venn diagram of downregulated miRs, identified in anti-IL-3R-EVs, antago-miR-24-3p EVs and pre-miR-214-3p EVs, are reported. The diagram shows an overlap of common miRs across different EVs d Venn diagram of upregulated miRs identified in anti-IL-3R-EVs, antago-miR-24-3p EVs and pre-miR-214-3p EVs. The diagram shows an overlap of common miRs among different EVs

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