Table 2 Molecular alterations that suppress EMT

From: Molecular alterations of cancer cell and tumour microenvironment in metastatic gastric cancer

Molecular alterations

Signalling pathways

References

ARID1A

–

[201]

CBL-B

AKT/ERK

[202]

CMTM3

STAT3/Twist1/EMT

[203]

DDAH1

WNT/β-Catenin

[204]

FBXL5

–

[205]

FBXW7

RhoA/p53

[33, 34, 206,207,208,209,210,211]

HOXB9

–

[30, 212, 213]

NMI

NFκB/p65

[214]

PAQR3

Raf/MAPK PI3K/AKT

[19, 215, 216]

PDK1

–

[217]

PPARγ

–

[218]

Rap1GAP

–

[219]

RKIP

Notch1

[220,221,222]

TOP1MT

–

[223]

miR-BART6-3p

–

[224]

miR-7

IGF

[225]

miR-22

–

[69]

miR-23b

Notch2

[226]

miR-128

PI3K/AKT

[227]

miR-143, miR-145

–

[228]

miR-200b

–

[229]

miR-216a

JAK2/STAT3

[230]

miR-338-3p

MET/AKT/PTEN

[25, 231,232,233]

miR-551b

–

[234]

miR-1271

–

[21]

miR-2392

–

[32]

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