Fig. 5 | Oncogene

Fig. 5

From: Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway

Fig. 5

MUC20 knockdown inhibits migration and invasion of PDAC cells co-cultured with PSCs. a MUC20 knockdown inhibited migration and invasion induced by pancreatic stellate cells (PSCs) in HPAC (upper) and HPAF-II (lower) cells. b MUC20 knockdown inhibited migration and invasion induced by PSC-conditioned medium. Cell migration and invasion were analysed by Transwell migration and Matrigel invasion assay, respectively. The left panel shows representative images of migrated and invaded cells. The right panel shows statistics of cell migration and invasion. Scale bars indicate 1 mm. Data are presented as mean (n = 3) ± SD. *P < 0.05; **P < 0.01

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