Fig. 6
ZNF185 is downregulated in HNSCC. a Immunohistochemical analysis of ZNF185 expression in normal skin and head and neck tissues. Scale bar: 100 µm. b Violin plots show ZNF185 mRNA level in normal (N) or tumour HNSCC (T) samples determined by microarray analysis. Different datasets from the GEO database were analysed. c Violin plot showing ZNF185 mRNA level in the samples of different grades from the TCGA HNSCC panel determined by RNA-seq (n = 520). d Dot plot showing the correlation between the mRNA levels of ZNF185 and CDH1 in the TCGA HNSCC panel (n = 520, R = 0.52). e GO terms for genes whose mRNA level is correlated with the ZNF185 mRNA level in the TCGA HNSCC panel (n = 520, R > 0.5). f ZNF185 expression in tissue microarray immunohistochemical analysis of different grades HNSCC samples. Scale bar: 500 µm. g Violin plot showing the distribution of H-index for ZNF185 level in the samples from (f)
