Fig. 6
The expression of Lin28A and ROCK2 were positively correlated and associated with poor prognosis in OC. a Both the mRNA expression of Lin28A (left) and ROCK2 (right) in OC were upregulated compared that of paracancerous adjacent normal ovarian epithelium tissues in the database GES18520. P = 0.0006 and P = 0.0152, respectively. b Representative images for the expression of Lin28A and ROCK2 was shown in OC tissue by immunohistochemistry analysis. Scale bar, 100 μm, 20 μm, respectively. c Pearson correlation analysis showed that the expression of Lin28A was positively correlated to that of ROCK2 in OC tissues. Pearson R = 0.8123, P < 0.0001. d Ten year survival analysis suggested the expression of Lin28A (top) and ROCK2 (down) negatively were co-related to the prognosis of OC patients using Kaplan–Meier survival analysis. P = 0.0170 and P = 0.0164, respectively
