Fig. 2 | Oncogene

Fig. 2

From: Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

Fig. 2

Novel fusion events. a Circos plot depicting examples of novel fusion events. Each case is represented by one color. Intergenic regions are indicted by colored circles. b Examples of candidate loss-of-function fusion events in the tumor-suppressor genes PTEN and ATM. c Models of candidate gain-of-function fusion events depicted at genome and protein level. Protein domains are labeled according to Pfam convention. Exons in each fusion partner are numbered

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