Fig. 1 | Oncogene

Fig. 1

From: Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma

Fig. 1

Neuroblastoma tumors with enhanced ribosome biogenesis activity are characterized by high MYCN expression, advanced stage disease, and poor prognosis. a Plot showing the distribution of High-RiBi and Low-RiBi neuroblastoma tumors in different INSS stages. b Boxplot showing MYCN expression in tumors defined by High-RiBi and Low-RiBi. High-RiBi tumors show significantly higher MYCN expression. Kaplan–Meier analysis showing overall c and event-free d survival of neuroblastoma patients defined by High-RiBi and Low-RiBi tumors. The analyses were performed on publically available data (Tumor Neuroblastoma SEQC-498-RNAseq) from R2: Genomic Analysis and Visualization Platform (http://r2.amc.nl)

Back to article page