Fig. 1 | Oncogene

Fig. 1

From: Tamoxifen mechanically deactivates hepatic stellate cells via the G protein-coupled estrogen receptor

Fig. 1

GPER activation in HSCs suppresses activation of MLC-2. a Representative images for immunofluorescence staining of HSCs, scale bar 50 µm. b Quantification of immunofluorescence staining for panel a. MFI mean fluorescence intensity, 12 fields of views with approximately 20 cells per field per condition. c Quantification of total and active RhoA, expressed as percentage of the total RhoA in the control condition, three biological samples analysed in three different experiments. All histogram bars represent mean ± sem, **P < 0.01,***P < 0.001. Anova and Tukey’s test for b and t-test for (c). Three experimental replicates in all panels

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