Fig. 10 | Oncogene

Fig. 10

From: Mono-ADP-ribosylation of H3R117 traps 5mC hydroxylase TET1 to impair demethylation of tumor suppressor gene TFPI2

Fig. 10

Bioinformatics analyses for abnormal methylation of TFPI2 and TET1 in colorectal cancer (CRC), as well as correlation and prognosis influence of transcript level of TFPI2 and TET1 of CRC and normal tissue. Methylated modification of TFPI2 and TET1 in normal and CRC was performed using MethHC database, while influence of TFPI2 and TET1 transcript level on overall survival and cancer stage classification of CRC as well as the correlation of these two genes was performed by Gene Expression Profiling Interactive Analysis (the cutoff % of high and low TFPI2/TET1 TPM was 50%)

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