Fig. 3 | Oncogene

Fig. 3

From: CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression

Fig. 3

CXCL14 mediates CD8+ T-cell infiltration into the tumor microenvironment. Representative image of MOE/E6E7Vector (a) and MOE/E6E7CXCL14 (b) tumor sections immunostained with anti-CD8α antibody (red), anti-cytokeratin antibody (green), and DAPI (blue) to identify CD8+ T cells and tumor tissues. CD8+ T cells were quantified as a number of CD8α-positive cells per total number of DAPI-positive cells across five representative images (c). P-values were calculated using Student’s t-test. *p < 0.05. Scale bars are 50 µm

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