Table 1 High-throughput screen identifying small molecule compounds that work in combination with CX-4945 to decrease MB growth
From: Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide
Compounds | Compound alone (% inhibition) | Compound + CX-4945 (% inhibition) | Activity |
|---|---|---|---|
CX-4945 | 51.4 | N/A | Inhibitor |
Temozolomidea | 48.1 | 74.3 | Inhibitor |
Raltitrexed | 47.2 | 70.2 | Inhibitor |
Flubendazolea | 61.4 | 68.1 | Inhibitor |
Ptersotilbene | 22.0 | 59.4 | Weak inhibitor |
Itavastatin Ca | 20.5 | 57.9 | Weak inhibitor |