Fig. 5
From: ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942
Expression of ABC-transporters is correlated with CDK7 inhibitor response in a cancer cell line panel. A panel of 854 cancer cell lines was screened with ICEC0942 and THZ2 and the GI50 values for each cell line plotted against their mRNA expression levels of ABCB1 (a, c) and ABCG2 (b, d). R = Pearson correlation coefficient
