Fig. 1: Forest plot represented the association between SNPrs17079281 and the risk of lung cancer overall and by histologic types and eQTL analysis. | Oncogene

Fig. 1: Forest plot represented the association between SNPrs17079281 and the risk of lung cancer overall and by histologic types and eQTL analysis.

From: SNP rs17079281 decreases lung cancer risk through creating an YY1-binding site to suppress DCBLD1 expression

Fig. 1: Forest plot represented the association between SNPrs17079281 and the risk of lung cancer overall and by histologic types and eQTL analysis.

a All lung cancer based on 4403 cases and 5336 controls. The studies were weighted according to the proportioned to the sample size in each study. Combined ORs and 95%CI were derived from the per-allele model. The result for the fix effects model (I2 = 0%, P = 0.98) were presented. b Association between rs17079281 and risk of squamous cell carcinoma, c adenocarcinoma. d The relative positions of SNP rs17079281 and DCBLD1 gene mapping to 6q22.1 were shown. The chromatin state of 6q22.1 locus in IMR90 was detailed with chromatin state segmentation track (ChromhMM). e, f eQTL analysis demonstrating the correlation between rs17079281 genotype and expression of DCBLD1 in lung squamous cell carcinoma (e) and lung adenocarcinoma (f).

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