Table 1 Number of apoptotic cells during EHT.

From: Phosphatidylinositol-3 kinase signaling controls survival and stemness of hematopoietic stem and progenitor cells

 

Embryos (n)

HSPCs

Apoptosis

Escapers

%Apoptosis

%Escapers

Wild-type

 Control

13

0

24

0

100

 LY294002

6

6

9

40

60

ptena−/−ptenb−/−

 Control

9

13

11

54

46

 LY 294002

5

0

21

0

100

  1. The number of cells undergoing apoptosis during EHT was determined in control and LY294002 (5 µM from 32 hpf onwards) treated wild-type and ptena−/−ptenb−/− embryos (35–48 hpf) by confocal time-lapse imaging. The number of embryos that was imaged is given as well as the number of apoptotic HSPCs or surviving HSPCs. The percentages of emerging or apoptotic HSPCs relative to the total number of HSPCs are also indicated.
Back to article page