Fig. 2: Comparison of the expression of ESR1, MYC, and Cyclin D1 in the cervical squamous epithelium among E2-injected Wt, HPV E6/E7 KI and WAPL Tg mice at 6 months after OVX.
From: WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7
Left panels show IHC analysis of ESR1, MYC, and Cyclin D1. Insets show higher magnification images. The scale bars represent 50 μm. Right panels show the graphs representing the rates of ESR1, MYC, and Cyclin D1 positive cells in the cervical squamous epithelium. The data were obtained from 6 mice for each group, and the representative images are shown. Error bars on the graphs represent S.D. of the mean. Statistical significance was calculated by Student t test. *p < 0.05. n.s. no significant difference.
