Fig. 4: HnRNPH1 is important for PRELID1P6-promoted glioma proliferation.
From: The pseudogene PRELID1P6 promotes glioma progression via the hnHNPH1-Akt/mTOR axis
A, B Knockdown of hnRNPH1 inhibited U138 and LNZ308 glioma cell proliferation. C Knockdown of hnRNPH1 inhibited the clone formation ability of U138 and LNZ308 glioma cells. D, E Knockdown of hnRNPH1 reversed the growth -promotion effect of PRELID1P6 overexpression in U138 and LNZ308 cells. F Overexpression of PRELID1P6 promoted the U138 and LNZ308 cell clone formation ability, while knockdown of hnRNPH1 reversed the growth-promotion effect of PRELID1P6 overexpression. G Overexpression of PRELID1P6 decreased U138 and LNZ308 cell apoptosis, while knockdown of hnRNPH1 reversed the inhibited apoptosis effect of PRELID1P6 overexpression. H, I Knockdown of PRELID1P6 inhibited U251 and U373 glioma cells growth ability, while overexpression of hnRNPH1 reversed the growth-inhibition effect of PRELID1P6 knockdown.
