Fig. 6: ZDHHC1 and p53 mutations determine p53 localization. | Oncogene

Fig. 6: ZDHHC1 and p53 mutations determine p53 localization.

From: Cancer cells escape p53’s tumor suppression through ablation of ZDHHC1-mediated p53 palmitoylation

Fig. 6: ZDHHC1 and p53 mutations determine p53 localization.The alternative text for this image may have been generated using AI.

(Left) Indirect immunofluorescent staining of p53WT in 293 T (with or without THP treatment), MCF7, EC109, HONE1, and A549 cells. (Right) Indirect immunofluorescent staining of p53 in cells carrying varied mutant p53. TE10 (p53-C242Y), CFPAC1 (p53-C242R), H2122 (p53-C176F), H1651 (p53-C176Y), MB231 (p53-R280K), and KYSE150 (p53-R248Q) were enlisted as experimental subjects. Pictures were photographed using confocal microscopy. THP: Pirarubicin.

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