Fig. 3: Mice deficient in Fdxr, Trp53, or both have a short life span and are prone to spontaneous tumors. | Oncogene

Fig. 3: Mice deficient in Fdxr, Trp53, or both have a short life span and are prone to spontaneous tumors.

From: Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1–SREBP pathway

Fig. 3: Mice deficient in Fdxr, Trp53, or both have a short life span and are prone to spontaneous tumors.The alternative text for this image may have been generated using AI.

A Kaplan–Meier survival curve for WT, Fdxr+/−, Trp53+/−, and Fdxr+/−;Trp53+/− mice. B Tumor spectra and penetrance in WT, Fdxr+/−, Trp53+/−, and Fdxr+/−;Trp53+/− mice. C Representative images of hematoxylin and eosin (H&E)-stained HCC in Fdxr+/−, Trp53+/−, and Fdxr+/−;Trp53+/− mice.

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